Nanotechnology Applications

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The future of the material sciences is closely linked to nanotechnology. And Nanotechnology engineering is a multi-disciplinary engineering field, which draws from and benefits areas such as materials science and engineering, chemistry, physics, biology, and medicine. The purpose of this presentation is to tell about nanotechnology applications in these fields.

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Nanotechnology Applications

The future of the material sciences is closely linked to nanotechnology. And Nanotechnology engineering is a multi-disciplinary engineering field, which draws from and benefits areas such as materials science and engineering, chemistry, physics, biology, and medicine. The purpose of this presentation is to tell about nanotechnology applications in these fields.

Introduction to Nanotechnology: Looking At Nanoparticles

Nanotechnology is defined as the study and use of structures between 1 nanometer and 100 nanometers in size. To give you an idea of how small that is, it would take eight hundred 100 nanometer particles side by side to match the width of a human hair.

 

Four Generations

Mihail (Mike) Roco has described four generations of nanotechnology development (see chart below). The current era, as Roco depicts it, is that of passive nanostructures, materials designed to perform one task. The second phase introduces active nanostructures for multitasking; for example, actuators, drug delivery devices, and sensors. The third generation, which we are just entering, is feature nanosystems with thousands of interacting components. A few years after that, the first integrated nanosystems are expected to be developed.

Introduction to Nanotechnology Applications

The ability to see nano-sized materials has opened up a world of possibilities in a variety of industries and scientific endeavors. Because nanotechnology is essentially a set of techniques that allow manipulation of properties at a very small scale, it can have many applications, such as the ones listed below.

Nanotechnology in Medicine

The use of nanotechnology in medicine offers some exciting possibilities. Some techniques are only imagined, while others are at various stages of testing, or actually being used today.

Nanotechnology in medicine involves applications of nanoparticles currently under development, as well as longer range research that involves the use of manufactured nano-robots to make repairs at the cellular level (sometimes referred to as nanomedicine).

Nanotechnology in Medicine Application:

  • Drug Delivery. One application of nanotechnology in medicine currently being developed involves employing nanoparticles to deliver drugs, heat, light or other substances to specific types of cells (such as cancer cells). Particles are engineered so that they are attracted to diseased cells, which allows direct treatment of those cells. This technique reduces damage to healthy cells in the body and allows for earlier detection of disease.
  • Therapy Techniques. Buckyballs may be used to trap free radicals generated during an allergic reaction and block the inflammation that results from an allergic reaction. Nanoparticles, when activated by x-rays, that generate electrons that cause the destruction of cancer cells to which they have attached themselves. This is intended to be used in place radiation therapy with much less damage to healthy tissue.  Nanobiotix has released preclinical results for this technique.
  • Diagnostic and Imaging Techniques. Quantum Dots (qdots) may be used in the future for locating cancer tumors in patients and in the near term for performing diagnostic tests in samples.
  • Anti-Microbial Techniques. One of the earliest nanomedicine applications was the use of nanocrystalline silver which is  as an antimicrobial agent for the treatment of wounds.
  • Cell Repair. Nanorobots could actually be programmed to repair specific diseased cells, functioning in a similar way to antibodies in our natural healing processes.

Nanotechnology in Medicine: Company Directory

Company Product
BioDelivery Sciences Oral drug delivery of drugs encapuslated in a nanocrystalline structure called a cochleate
CytImmune Gold nanoparticles for targeted delivery of drugs to tumors
Invitrogen Qdots for medical imaging
Smith and Nephew Antimicrobial wound dressings using silver nanocrystals
Luna Inovations Bucky balls to block inflammation by trapping free radicals
NanoBio Nanoemulsions for nasal delivery to fight viruses (such as the flu and colds) or through the skin to fight bacteria
NanoBioMagnetics Magnetically responsive nanoparticles for targeted drug delivery and other applications
Nanobiotix Nanoparticles that target tumor cells, when irradiated by xrays the nanoparticles generate electrons which cause localized destruction of the tumor cells.
Nanospectra  AuroShell particles (nanoshells) for thermal destruction of cancer tissue
Nanosphere Diagnostic testing using gold nanoparticles to detect low levels of proteins indicating particular diseases
Nanotherapeutics Nanoparticles for improving the performance of drug delivery by oral or nasal methods 
Oxonica Diagnostic testing using gold nanoparticles (biomarkers)
T2 Biosystems Diagnostic testing using magnetic nanoparticles
Z-Medica Medical gauze containing aluminosilicate nanoparticles which help blood clot faster in open wounds.
Sirnaomics Nanoparticle enhanced techniques for delivery of siRNA
Makefield Therapeutics Nanoparticle cream for delivery of nitric oxide gas to treat infection
DNA Medicine Institute Diagnostic testing system
NanoViricides Drugs called nanoviricides™ designed to attack virus particles
NanoMedia Targeted drug delivery
Taiwan Liposome Drug delivery using lipsomes
Traversa Therapeutics Delivery of siRNA molecules
Nano Science Diagnostics Diagnostic testing system

Nanotechnology in Electronics (Nanoelectronics)

How can nanotechnology improve the capabilities of electronic components?

Nanoelectronics holds some answers for how we might increase the capabilities of electronics devices while we reduce their weight and power consumption. Some of the nanoelectronics areas under development, which you can explore in more detail by following the links provided in the next section, include the following topics.

Improving display screens on electronics devices. This involves reducing power consumption while decreasing the weight and thickness of the screens.

Increasing the density of memory chips. Researchers are developing a type of memory chip with a projected density of one terabyte of memory per square inch or greater.

Reducing the size of transistors used in integrated circuits. One researcher believes it may be possible to "put the power of all of today's present computers in the palm of your hand".

Nanoelectronics: Company Directory

Company Products or Projects
Everspin Technologies Magnetoresistive Random Access Memory (MRAM)
HP Self-assembled nanostructures
IBM Nanophotonics
Intel Integrated circuits with nano-sized features
California Molecular  
Electronics Corp.
Molecule sized switches and other devices
Unidym Nanotube based transparent conductive film for use in applications such as LCD displays and e-paper
Imec Developing CMOS technology for IC's using sub-22nm geometry

Environmental Nanotechnology

Nanotechnology is being used in several applications to improve the environment. This includes cleaning up existing pollution, improving manufacturing methods to reduce the generation of new pollution, and making alternative energy sources more cost effective.

Air Pollution and Nanotechnology

How can nanotechnology reduce air pollution?

There are two major ways in which nanotechnology is being used to reduce air pollution: catalysts, which are currently in use and constantly being improved upon; and nanostructured membranes, which are under development.

Water Pollution and Nanotechnology

How can nanotechnology be used to reduce water pollution?

Nanotechnology is being used to develop solutions to three very different problems in water quality.

One challenge is the removal of industrial water pollution from ground water. Nanoparticles can be used to convert the contaminating chemical through a chemical reaction to make it harmless.

Another challenge is the removal of salt or metals from water. A deionization method using electrodes composed of nano-sized fibers shows promise for reducing the cost and energy requirements of turning salt water into drinking water.

The third problem concerns the fact that standard filters do not work on virus cells. A filter only a few nanometers in diameter is currently being developed that should be capable of removing virus cells from water.

Nanotechnology in Space       

Nanotechnology may hold the key to making space flight more practical. Advancements in nanomaterials make lightweight solar sails and a cable for the space elevator possible. By significantly reducing the amount of rocket fuel required, these advances could lower the cost of reaching orbit and traveling in space. In addition, new materials combined with nanosensors and nanorobots could improve the performance of spaceships, spacesuits, and the equipment used to explore planets and moons, making nanotechnology an important part of the ‘final frontier.’

Space Flight and Nanotechnology: Applications under Development

Researchers are looking into the following applications of nanotechnology in space flight:

  • Using carbon nanotubes to make the cable needed for the space elevator, a system which could significantly reduce the cost of sending material into orbit.
  • Including layers of bio-nano robots in spacesuits. The outer layer of bio-nano robots would respond to damages to the spacesuit, for example to seal up punctures. An inner layer of bio-nano robots could respond if the astronaut was in trouble, for example by providing drugs in a medical emergency.
  • Employing materials made from carbon nanotubes to reduce the weight of spaceships while retaining or even increasing the structural strength.

     

  • Using carbon nanotubes to build lightweight solar sails that use the pressure of light from the sun reflecting on the mirror-like solar cell to propel a spacecraft. This solves the problem of having to lift enough fuel into orbit to power spacecraft during interplanetary missions.

  • Working with nanosensors to monitor the levels of trace chemicals in spacecraft to monitor the performance of life support systems.

Nanotechnology in Food

How is Nanotechnology being used in Food Science?

Nanotechnology is having an impact on several aspects of food science, from how food is grown to how it is packaged. Companies are developing nanomaterials that will make a difference not only in the taste of food, but also in food safety, and the health benefits that food delivers.

Food Science: Nanotechnology Company Directory

Company Product
Nancor Bottles, cartons and films containing clay nanocomposite that act as a barrier to the passage of gasses or odors
Bayer Polymers Plastic film containing silicate nanoparticles that provides a barrier to gasses or moisture
AquaNova Nanoparticles for delivery of vitamins or other nutrients in food and beverages without affecting the taste or appearance.
Nano Science Diagnostics Rapid testing for contaminates in food

Food Science: Current Nanotechnology Applications

Clay nanocomposites are being used to provide an impermeable barrier to gasses such as oxygen or carbon dioxide in lightweight bottles, cartons and packaging films.

 Nanomer particles protruding from a plasma-etched polymer matrix

Storage bins are being produced with silver nanoparticles embedded in the plastic. The silver nanoparticles kill bacteria from any material that was previously stored in the bins, minimizing health risks from harmful bacteria.

Food Science: Nanotechnology Applications under Development

Nanoparticles are being developed that will deliver vitamins or other nutrients in food and beverages without affecting the taste or appearance. These nanoparticles actually encapsulate the nutrients and carry them through the stomach into the bloodstream.

Researchers are using silicate nanoparticles to provide a barrier to gasses (for example oxygen), or moisture in a plastic film used for packaging. This could reduce the possibly of food spoiling or drying out.

Zinc oxide nanoparticles can be incorporated into plastic packaging to block UV rays and provide anti bacterial protection, while improving the strength and stability of the plastic film.

Nanosensors are being developed that can detect bacteria and other contaminates, such as salmonella, at a packaging plant. This will allow for frequent testing at a much lower cost than sending samples to a lab for analysis. This point-of-packaging testing, if conducted properly, has the potential to dramatically reduce the chance of contaminated food reaching grocery store shelves.

"Interactive" foods are being developed that would allow you to choose the desired flavor and color. Nanocapsules that contain flavor or color enhancers are embedded in the food; inert until a hungry consumer triggers them. The method hasn't been published, so it will be interesting to see how this particular trick is accomplished.

Researchers are also working on pesticides encapsulated in nanoparticles; that only release pesticide within an insect's stomach, minimizing the contamination of plants themselves.

Nanotechnology in Fabrics

How can nanotechnology improve fabric?

Making composite fabric with nano-sized particles or fibers allows improvement of fabric properties without a significant increase in weight, thickness, or stiffness as might have been the case with previously-used  techniques. For example incorporating nano-whiskers into fabric used to make pants produces a lightweight water and stain repellent material.

Fabric: Current Nanotechnology Applications

    • Nanowhiskers that cause water to bead up, making the fabric water and stain resistant.
    • Silver nanoparticles in fabric that kills bacteria making clothing odor- resistant.
    • Nanopores providing superior insulation for shoe inserts in cold weather. 
    • Nanoparticles that provide a "lotus plant" effect for fabric used awnings and other material left out in the weather, causing dirt to rinse off in the rain.

Fabric: Nanotechnology Company Directory

Company Product Advantage
Nano-tex Fabric enhanced with nanowhiskers Water and stain resistant
Aspen Aerogel Fabric enhanced with nanopores Insulates against heat or chill
BASF Fabric enhanced with nanoparticles Dirt rinses off in rain, similar to property of the lotus plant
NanoHorizons Fabric enhanced with  silver nanoparticles Reduces odors
Schoeller Technologies Fabric enhanced with nanoparticles (NanoSphere®) Water and stain resistant
Nano Group Fabric enhanced with various nano treatments Liquid and stain resistant, UV protection, etc
Odegon Technologies Fabric enhanced with nano-porous material that absorbs underarm odors  

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